Recombinant protein production associated growth inhibition results mainly from transcription and not from translation.

Published in: Microbial cell factories (2020)

The so-called metabolic burden of recombinant protein production is mainly attributed to transcription but can be enhanced through translation and those processes following translation (e.g. protein folding and degradation, heat-shock responses).

Keyphrases

heat shock
transcription factor
protein protein
heat stress
amino acid
binding protein
heat shock protein
single molecule
oxidative stress
molecular dynamics simulations
small molecule