Characteristics and Predictors of Apparent Treatment Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data.
Eissa JafariRhonda M Cooper-DeHoffMark B EffronWilliam R HoganCaitrin W McDonoughPublished in: medRxiv : the preprint server for health sciences (2023)
Large, diverse real-world populations showed a similar prevalence of aTRH, 16.7% in OneFlorida and 11.3% in REACHnet, compared to those observed from other cohorts.Patients classified as apparent treatment resistant hypertension were significantly older and had a higher prevalence of comorbid conditions such as diabetes, dyslipidemia, coronary artery disease, heart failure with preserved ejection fraction, and chronic kidney disease stages 1-3.Within diverse, real-world populations, the strongest predictors for apparent treatment resistant hypertension were black race, higher body mass index, heart failure, chronic kidney disease, and diabetes.
Keyphrases
- end stage renal disease
- chronic kidney disease
- electronic health record
- blood pressure
- heart failure
- peritoneal dialysis
- body mass index
- coronary artery disease
- type diabetes
- diffusion weighted imaging
- cardiovascular disease
- risk factors
- physical activity
- clinical decision support
- glycemic control
- ejection fraction
- newly diagnosed
- genetic diversity
- prognostic factors
- weight gain
- percutaneous coronary intervention
- coronary artery bypass grafting
- cardiovascular events
- acute coronary syndrome
- artificial intelligence
- contrast enhanced
- transcatheter aortic valve replacement
- data analysis