Immunological impact of chemotherapy on the tumor microenvironment in gastric cancer.

Qing WeiQi XuXing YuanJing-Jing LiLei ChenCong LuoXiu ZhuJie-Er Ying

Published in: Journal of surgical oncology (2021)

Chemotherapy in GC is useful to induce CD3+ and CD8+ T lymphocytes as well as CD68+ and CD163+ macrophages in the tumor microenvironment in combination with its direct cytotoxic effects. These results indicate that chemotherapy may play a role in tumor immune microenvironment remodeling.

Keyphrases

locally advanced
nk cells
stem cells
squamous cell carcinoma
radiation therapy
mass spectrometry
chemotherapy induced