Transcriptomes of Major Proximal Tubule Cell Culture Models.

Syed J Khundmiri Lihe ChenEleanor D LedererChin-Rang YangMark A Knepper

Published in: Journal of the American Society of Nephrology : JASN (2020)

No cell line fully matched the transcriptome of native proximal tubule cells. However, some of the lines tested are suitable for the study of particular metabolic and transport processes seen in the proximal tubule.

Keyphrases

induced apoptosis
single cell
cell cycle arrest
rna seq
genome wide
cell death
oxidative stress
pi k akt