Pyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis.

Anne SixKhedidja MosbahiMadhuri BargeColin KleanthousThomas EvansDaniel C Walker

Published in: The Journal of antimicrobial chemotherapy (2021)

Pyocins S5 and AP41 show in vivo biological activity and can improve survival in two models of P. aeruginosa infection. They hold promise as novel antimicrobial agents for treatment of MDR infections with this microbe.

Keyphrases

pseudomonas aeruginosa
cystic fibrosis
staphylococcus aureus
intensive care unit
acute kidney injury
multidrug resistant
biofilm formation
big data
machine learning
combination therapy
deep learning
candida albicans