Possible roles of genetic variations in chemotherapy related cardiotoxicity in pediatric acute lymphoblastic leukemia and osteosarcoma.

Judit C SágiBálint EgyedAndrea KelemenNóra KutszegiMárta HegyiAndrás GézsiMartina Ayaka HerlitschkeAndrea RzepielLili E FodorGábor OttóffyGábor T KovácsDániel J ErdélyiCsaba SzalaiÁgnes F Semsei

Published in: BMC cancer (2018)

Genetic variants in transporters and metabolic enzymes might modulate the individual risk to cardiac toxicity after chemotherapy.

Keyphrases

acute lymphoblastic leukemia
locally advanced
allogeneic hematopoietic stem cell transplantation
left ventricular
squamous cell carcinoma
copy number
chemotherapy induced
heart failure
acute myeloid leukemia
dna methylation