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Crocin Improves Oxidative Stress by Potentiating Intrinsic Anti-Oxidant Defense Systems in Pancreatic Cells During Uncontrolled Hyperglycemia.

Habib YaribeygiAli NoroozadehMohammad Taghi MohammadiThomas P JohnstonAmirhossein Sahebkar
Published in: Journal of pharmacopuncture (2019)
Based on our results, it is concluded that uncontrolled hyperglycemia can weaken the anti-oxidant defense system and cause the development of OS. Also, crocin can improve OS in pancreatic cells by potentiating the anti-oxidant defense system.
Keyphrases
  • induced apoptosis
  • oxidative stress
  • cell cycle arrest
  • endoplasmic reticulum stress
  • diabetic rats
  • signaling pathway
  • dna damage
  • innate immune
  • cell death
  • ischemia reperfusion injury
  • pi k akt
  • heat stress