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Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice.

Yuan TianBipin RimalJordan E BisanzWei GuiTrenton M WolfeImhoi KooIain A MurrayShaneice K NettlefordShigetoshi YokoyamaFangcong DongSergei KoshkinK Sandeep PrabhuPeter J TurnbaughSeth T WalkGary H PerdewAndrew D Patterson
Published in: Environmental health perspectives (2024)
These data obtained in a mouse model point to the complex effects of POPs on the host and microbiota, providing strong evidence that early life, short-term, and self-limiting POP exposure can adversely impact the microbiome, with effects persisting into later life with associated health implications. https://doi.org/10.1289/EHP13356.
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