Oleacein Attenuates the Pathogenesis of Experimental Autoimmune Encephalomyelitis through Both Antioxidant and Anti-Inflammatory Effects.

Beatriz Gutiérrez-MirandaIsabel GallardoEleni MelliouIsabel CaberoYolanda ÁlvarezProkopios MagiatisMarita HernándezMaria Luisa Nieto

Published in: Antioxidants (Basel, Switzerland) (2020)

Altogether, our results show that the antioxidant and anti-inflammatory OLE has neuroprotective effects in the CNS of EAE mice, pointing out this natural product as a candidate to consider for research on MS treatments.

Keyphrases

anti inflammatory
oxidative stress
mass spectrometry
multiple sclerosis
ms ms
blood brain barrier
high fat diet induced
type diabetes
metabolic syndrome
skeletal muscle
insulin resistance