Analysis of the effect of CPAP on hemodynamics using clinical data and a theoretical model: CPAP therapy decreases cardiac output mechanically but increases it via afterload reduction.
Masayoshi YoshidaHilmi R DajaniShin-Ichi AndoShuji ShimizuMiodrag BolicVoicu GrozaPublished in: Sleep medicine (2023)
CPAP would increase CO only where PVR can be reduced by CPAP therapy, especially in the case with hypervolemia and/or low RV systolic function. Understanding the underlying mechanism should help identify the patients for whom NIPPV would be effective.
Keyphrases
- obstructive sleep apnea
- positive airway pressure
- sleep apnea
- end stage renal disease
- left ventricular
- mycobacterium tuberculosis
- ejection fraction
- heart failure
- newly diagnosed
- chronic kidney disease
- blood pressure
- peritoneal dialysis
- prognostic factors
- stem cells
- machine learning
- bone marrow
- cell therapy
- artificial intelligence