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Nidogen-2 is a Novel Endogenous Ligand of LGR4 to Inhibit Vascular Calcification.

Yufei ChenChenfeng MaoRui GuRujia ZhaoWeihao LiZihan MaYiting JiaFang YuJian LuoYi FuJinpeng SunWei Kong
Published in: Circulation research (2022)
Nidogen-2 is a novel endogenous ligand of LGR4 that biased activated Gαq- PKCα-AMPKα1 signaling and inhibited vascular calcification.
Keyphrases
  • chronic kidney disease
  • skeletal muscle
  • protein kinase