Induced pluripotent stem cells from urine of Duchenne muscular dystrophy patients.
Fareeha Faizan GhoriMohsin WahidPublished in: Pediatrics international : official journal of the Japan Pediatric Society (2021)
This integration-free, feeder-free, efficient, and reproducible reprogramming method employed UDCs. Urine is a low-cost, non-invasive, painless, and repeatable source of rapidly expandable cells from children and morbid individuals for obtaining autologous cells for drug-assays and disease-modelling, suitable for DMD and other debilitating diseases.
Keyphrases
- duchenne muscular dystrophy
- low cost
- induced pluripotent stem cells
- end stage renal disease
- induced apoptosis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- young adults
- bariatric surgery
- muscular dystrophy
- bone marrow
- prognostic factors
- cell cycle arrest
- high throughput
- cell therapy
- cell death
- adverse drug