HOXA13 promotes gastric cancer progression partially via the FN1-mediated FAK/Src axis.

Published in: Experimental hematology & oncology (2022)

Our results show that HOXA13 is a positive regulator of the FAK/Src axis mediated by FN1 in GC and promotes GC progression. Thus, targeting HOXA13, together with FN1, may provide a novel prospective anticancer strategy.

Keyphrases

long non coding rna
long noncoding rna
tyrosine kinase
cell migration
transcription factor
cancer therapy
mass spectrometry
drug delivery