P63-related disorders: Dermatological characteristics in 22 patients.

Alexia MaillardCaroline AlbyEric GabisonSerge DoanFrédéric CauxChristine BodemerSmail Hadj Rabia

Published in: Experimental dermatology (2020)

In P63-related ectodermal dysplasias (ED), the clinical characteristics focus on extra-cutaneous manifestations. The dermatological phenotype remains incompletely characterized. We report the dermatological features of 22 patients carrying a TP63 mutation. Erosions, erythroderma and pigmentary anomalies are characteristics of P63-related ED. Our data suggest that patients might be classified into two major P63-related disorders: AEC and EEC. RHS and ADULT represent mild AEC and EEC forms, respectively.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
emergency department
peritoneal dialysis
prognostic factors
patient reported outcomes
electronic health record