Characteristics and Survival Outcomes of Patients With Metastatic RET Fusion-Positive Solid Tumors Receiving Non-RET Inhibitor Standards of Care in a Real-World Setting.
Allan HackshawOtto FajardoUrania DafniAndré B P van KuilenburgPilar GarridoSalvatore SienaMatthew H TaylorWalter BordognaChristos NikolaidisPublished in: JCO precision oncology (2024)
fusions represent a negative prognostic factor in patients with metastatic solid tumors and highlight the need for wider genomic testing and use of RET-specific TKIs that could improve patient outcomes. Our study also highlights the value of real-world data when studying rare cancers or cancers with rare genomic alterations.