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Characteristics and Survival Outcomes of Patients With Metastatic RET Fusion-Positive Solid Tumors Receiving Non-RET Inhibitor Standards of Care in a Real-World Setting.

Allan HackshawOtto FajardoUrania DafniAndré B P van KuilenburgPilar GarridoSalvatore SienaMatthew H TaylorWalter BordognaChristos Nikolaidis
Published in: JCO precision oncology (2024)
fusions represent a negative prognostic factor in patients with metastatic solid tumors and highlight the need for wider genomic testing and use of RET-specific TKIs that could improve patient outcomes. Our study also highlights the value of real-world data when studying rare cancers or cancers with rare genomic alterations.
Keyphrases
  • prognostic factors
  • copy number
  • healthcare
  • palliative care
  • electronic health record
  • big data
  • gene expression
  • dna methylation
  • chronic pain
  • childhood cancer
  • genome wide
  • data analysis
  • deep learning