Diet-induced weight loss in obese/diabetic mice normalizes glucose metabolism and promotes functional recovery after stroke.
Dimitra KarampatsiAlexander ZabalaUlrika WilhelmssonDoortje DekensEllen VercalsterenMartin LarssonThomas NyströmMilos PeknyCesare PatroneVladimer DarsaliaPublished in: Cardiovascular diabetology (2021)
The global diabetes epidemic will dramatically increase the number of people in need of post-stroke treatment and care. Our results suggest that diet-induced weight loss leading to pre-stroke normalization of glucose metabolism has great potential to reduce the sequelae of stroke in the diabetic population.
Keyphrases
- weight loss
- bariatric surgery
- glycemic control
- atrial fibrillation
- type diabetes
- roux en y gastric bypass
- gastric bypass
- healthcare
- cardiovascular disease
- palliative care
- obese patients
- quality improvement
- weight gain
- metabolic syndrome
- human health
- body mass index
- skeletal muscle
- blood brain barrier
- physical activity
- health insurance
- replacement therapy