Immune profiling of premalignant lesions in patients with Peutz-Jeghers syndrome.
Zhongyue LiuBoda WuXiaoliu ShiJunfeng ZhouHui HuangZhihong LiMei YangPublished in: United European gastroenterology journal (2024)
The findings suggest an immunobiological foundation for the increased cancer susceptibility in PJS patients, paving the way for potential immune therapy applications in this population. Furthermore, utilizing PJS as a model may facilitate the exploration of immune evasion mechanisms, benefiting both PJS and cancer patients.