DNA-nanohydrogel self-assembled gold nanoparticles: co-profiling of multiple small molecule reductants in rat brain.

DNA nanohydrogel assembled AuNPs were proposed as a high-throughput multidimensional sensing strategy for small molecule reductant profiling in rat brain. The equilibrium among AuNPs, DNA nanohydrogel and targets produced a unique fingerprint-like pattern for differentiating the reducing capacity.