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Radiation Retinopathy: Detection and Management Strategies.

Niroj Kumar SahooRicha RanjanMudit TyagiHitesh AgrawalSubhakar Reddy
Published in: Clinical ophthalmology (Auckland, N.Z.) (2021)
A gradual shift in trend from primary enucleation to globe salvaging radiation therapy for the management of ocular tumors has resulted in the rise of several post-treatment ocular complications including radiation retinopathy. Radiation retinopathy is a chronic, progressive, and occlusive vasculopathy that can manifest anytime between 1 month to 15 years after starting radiation therapy. The aim of treatment in most of these cases is to prevent further vision loss. Treatment options such as laser photocoagulation, anti-vascular endothelial growth factor and intraviral steroids have been described. However, despite several advances in diagnostic and therapeutic modalities, a significant proportion of eyes with radiation retinopathy eventually go blind. This review summarises some of the clinical features, investigative modalities, and recent therapeutic strategies used in the management of radiation retinopathy.
Keyphrases
  • vascular endothelial growth factor
  • radiation therapy
  • radiation induced
  • multiple sclerosis
  • optical coherence tomography
  • high resolution
  • high speed
  • drug induced