Epigenetic Association Analyses and Risk Prediction of RLS.

Philip HarrerNazanin Mirza-SchreiberVanessa MandelSigrun RoeberAmbra StefaniShamsun NaherMatias WagnerChristian GiegerMelanie WaldenbergerAnnette PetersBirgit HöglJochen HermsBarbara SchormairChen ZhaoJuliane WinkelmannKonrad Oexle

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

DNA methylation supports the notion of altered neurodevelopment in RLS. Epigenetic risk scores are reliably associated with RLS but require even higher accuracy to be useful as biomarkers. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

dna methylation
gene expression
genome wide
copy number
meta analyses