Placental Methylglyoxal in Preeclampsia: Vascular and Biomarker Implications.

Philippe VangriekenSalwan Al-NasiryAlex H V RemelsPaul M H SchiffersEmma B N J Janssen Stefanie Nass Jean L J M ScheijenMarc E A SpaandermanMiranda T Schram

Published in: Hypertension (Dallas, Tex. : 1979) (2024)

This study reveals the accumulation of placental MGO in preeclampsia and upon exposure to hypoxia, demonstrates how MGO can contribute to vascular impairment, and highlights plasma CML and MG-H1 levels as promising early biomarkers for preeclampsia.

Keyphrases

early onset
pregnancy outcomes