N6-Methyladenosine RNA modification in cerebrospinal fluid as a novel potential diagnostic biomarker for progressive multiple sclerosis.

Fei YeTianzhu WangXiaoxin WuJie LiangJiaoxing LiWenli Sheng

Published in: Journal of translational medicine (2021)

The dynamic modification of m6A RNA methylation is involved in the progression of MS and could potentially represent a novel CSF biomarker for diagnosing MS and distinguishing PMS from RRMS in the early stages of the disease.

Keyphrases

multiple sclerosis
cerebrospinal fluid
white matter
mass spectrometry
ms ms
genome wide
dna methylation
nucleic acid
risk assessment