Variations of C14ORF39 and SYCE1 identified in idiopathic premature ovarian insufficiency and nonobstructive azoospermia.

Dong HouChencheng YaoBingying XuWei LuoHanni KeZheng LiYingying Qin Ting Guo

Published in: The Journal of clinical endocrinology and metabolism (2021)

Our study identified novel pathogenic variations of C14ORF39 and SYCE1 in sporadic patients with POI or NOA, highlighting the essential role of SC genes in the maintenance of ovarian and testicular function.

Keyphrases

genome wide
late onset
gene expression
genome wide identification