Decreases in hepatokine Fetuin-A levels are associated with hepatic hypoperfusion and predict cardiac outcomes in patients with heart failure.

Yusuke TomitaTomofumi MisakaAkiomi YoshihisaYasuhiro IchijoShinji IshibashiMitsuko MatsudaYukio YamaderaHimika OharaYukiko SugawaraYu HotsukiKoichiro WatanabeFumiya AnzaiYu SatoTakamasa SatoMasayoshi OikawaAtsushi KobayashiYasuchika Takeishi

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2022)

Liver-derived hepatokine Fetuin-A may be a novel target involved in the cardio-hepatic interactions, as well as a useful biomarker for predicting the prognosis in patients with HF.

Keyphrases

left ventricular
heart failure
metabolic syndrome
skeletal muscle
insulin resistance