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Six months survival and risk factors for attrition for patients detected with cryptococcal antigenemia through screening in Malawi.

Master R O ChisaleAlex JordanPocha S KamudumuliBernard MvulaMichael OdoAlice MaidaJames KanduluBen ChilimaFrank W SinyizaPauline KatunduHsin-Yi LeeRebecca MteghaTsung-Shu Joseph WuJoseph BitirinyoRose NyirendaThoko KaluaGreg GreeneTom Chiller
Published in: PloS one (2023)
Overall, our findings indicate a need for routine access to CrAg screening and pre-emptive fluconazole treatment as a way to detect cryptococcal antigenemia and prevent CM in outpatient and inpatient settings. Rapid access to diagnosis and treatment for cryptococcal meningitis (CM) with gold-standard antifungals is needed to improve survival of patients with advanced HIV in Malawi.
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