Disturbances of the transfer of cholesterol to high-density lipoprotein (HDL) in patients with peripheral artery disease with or without type 2 diabetes mellitus.
Flávio Roberto Cavalleiro de Macedo RibeiroCarolina Heitmann Mares Azevedo RibeiroThauany Martins TavoniErica Dos Santos SargesFatima Rodrigues FreitasNoedir Antonio Groppo StolfRoberto Kalil FilhoRaul Cavalcante MaranhãoPublished in: Vascular medicine (London, England) (2021)
Deficient cholesterol transfer to HDL may play a role in PAD pathogenesis. Since UC transfer to HDL was lower in PAD + DM compared to PAD alone, it is possible that defective HDL metabolism may contribute to the higher PAD incidence in patients with T2DM.Keywords.