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cRGDfK-Grafted Small-Size Quercetin Micelles For Enhancing Therapy Efficacy Of Active Ingredient From The Chinese Medicinal Herb.

Pengcheng XuHaisheng WangHongxiang HuYong YeYu DongSuxin LiDong MeiZhaoming GuoDan WangYanxue SunTengfei YuJunchan QiaoQiang Zhang
Published in: International journal of nanomedicine (2019)
Quercetin as a natural product has triggered increasing interest in the antitumor field. In this study, cRGDfK-modified DSPE-PEG micelles significantly optimized quercetin therapeutic efficacy and pulmonary toxicity as well as lowered systemic toxicity.
Keyphrases
  • drug delivery
  • drug release
  • cancer therapy
  • oxidative stress
  • pulmonary hypertension
  • hyaluronic acid
  • stem cells
  • cell therapy