Ketogenic treatment reduces the percentage of a LHON heteroplasmic mutation and increases mtDNA amount of a LHON homoplasmic mutation.
Sonia EmperadorEster López-GallardoCarmen Hernández-AinsaMouna HabbaneJulio MontoyaM Pilar Bayona-BafaluyEduardo Ruiz-PesiniPublished in: Orphanet journal of rare diseases (2019)
These results suggest that ketogenic diet could be a therapeutic strategy for Leber hereditary optic neuropathy.