Unraveling Immunological Dynamics: HPV Infection in Women-Insights from Pregnancy.
Carmen Elena CondratDragos CretoiuViorica Elena RadoiDana Mihaela MiheleMihaela TovaruCristian Ioan BordeaSilviu Cristian VoineaNicolae SuciuPublished in: Viruses (2023)
During pregnancy, hormonal and immune adaptations are vital for supporting the genetically distinct fetus during elevated infection risks. The global prevalence of HPV necessitates its consideration during pregnancy. Despite a seemingly mild immune response, historical gestational viral infections underscore its significance. Acknowledging the established HPV infection risks during pregnancy, our review explores the unfolding immunological changes in pregnant women with HPV. Our analysis aims to uncover strategies for safely modulating the immune system, mitigating adverse pregnancy consequences, and enhancing maternal and child health. This comprehensive narrative review delves into the existing knowledge and studies on this topic.
Keyphrases
- pregnancy outcomes
- high grade
- cervical cancer screening
- immune response
- pregnant women
- polycystic ovary syndrome
- preterm birth
- healthcare
- human health
- birth weight
- weight gain
- risk factors
- dendritic cells
- emergency department
- risk assessment
- toll like receptor
- signaling pathway
- insulin resistance
- metabolic syndrome
- weight loss
- data analysis