Impact of Androgen Deprivation on Oxidative Stress and Antioxidant Status in Nigerian Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy.

Iya Eze BasseyBukola Abosede EmodiUwem Okon AkpanIdorenyin Francesca Akpan IyakndueEdim Azubuike AnakebeBassey Edward Icha Henry Afamuefuna EfobiAkan Joshua NtinyaAlphonsus Ekpe Udoh

Published in: JCO global oncology (2021)

This study demonstrated that patients with CaP have higher levels of TPP, MDA, and NO and lower levels of TAC compared with men without CaP. In addition, even in patients with CaP undergoing treatment, TPP and MDA levels remained high.

Keyphrases

oxidative stress
prostate cancer
breast cancer cells
radical prostatectomy
dna damage
stem cells
induced apoptosis
cell death
mesenchymal stem cells
cell cycle arrest
signaling pathway
middle aged
cell therapy
replacement therapy