Early onset as a marker for disease severity in facioscapulohumeral muscular dystrophy.

Rianne J M Goselink Karlien MulCaroline R van KernebeekRichard J L F LemmersSilvère M van der MaarelTim H A SchreuderCorrie E ErasmusGeorge W PadbergJeffrey M StatlandNicol C VoermansBaziel G M van Engelen

Published in: Neurology (2018)

Patients with early-onset FSHD more often have severe muscle weakness and systemic features. The disease severity is greater than in patients with classic-onset FSHD who are matched for disease duration, suggesting that the progression is faster in early-onset patients.

Keyphrases

early onset
muscular dystrophy
late onset
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
duchenne muscular dystrophy
skeletal muscle
prognostic factors