Macrophage-derived MLKL in alcohol-associated liver disease: Regulation of phagocytosis.

Xiaoqin WuXiude FanMegan R McMullenTatsunori MiyataAdam KimVai PathakJianguo WuLe Z DayJosiah E HardestyNicole WelchJaividhya DasarathyDaniela S AllendeArthur J McCulloughJon M JacobsDaniel M RotroffSrinivasan DasarathyLaura E Nagy

Published in: Hepatology (Baltimore, Md.) (2022)

Together, these data indicate that myeloid MLKL restricts ethanol-induced liver inflammation and injury by regulating hepatic immune cell homeostasis and macrophage phagocytosis.

Keyphrases

adipose tissue
oxidative stress
diabetic rats
high glucose
electronic health record
dendritic cells
bone marrow
acute myeloid leukemia
endothelial cells
immune response
deep learning