Neurodegeneration and humoral response proteins in cerebrospinal fluid associate with pediatric-onset multiple sclerosis and not monophasic demyelinating syndromes in childhood.
Arlette L BruijstensChristoph StinglCoşkun GüzelMarcel P StoopYu Yi M WongE Daniëlle van PeltBrenda L BanwellAmit Bar-OrTheo M LuiderRinze Frederik Neuteboomnull nullPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
This exploratory study identified several CSF proteins associated with POMS and not mADS, potentially reflecting neurodegeneration, compensatory neuroprotection, and humoral response in POMS. The proteins associated with POMS highly correlated with age at CSF sampling.