Ubiquitin-specific protease 38 promotes inflammatory atrial fibrillation induced by pressure overload.
Zheng XiaoYucheng PanBin KongHong MengWei ShuaiHe HuangPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
Overall, our study indicates that USP38 promotes pressure overload-induced AF through targeting NF-κB/NLRP3-mediated inflammatory responses.
Keyphrases
- atrial fibrillation
- oxidative stress
- signaling pathway
- diabetic rats
- heart failure
- left atrial
- high glucose
- catheter ablation
- oral anticoagulants
- small molecule
- lps induced
- left atrial appendage
- cancer therapy
- nuclear factor
- direct oral anticoagulants
- pi k akt
- cell proliferation
- coronary artery disease
- toll like receptor
- inflammatory response