Assessment of treatment responses in children and adolescents with Ewing sarcoma with metabolic tumor parameters derived from 18F-FDG-PET/CT and circulating tumor DNA.

Christian SchmidkonzManuela KrumbholzArmin AtzingerMichael CordesTheresa Ida GoetzOlaf PrantePhilipp RittChristiane SchaeferAbbas AgaimyWolfgang HartmannClaudia RössigBirgit FröhlichTobias BäuerleUta DirksenTorsten KuwertMarkus Metzler

Published in: European journal of nuclear medicine and molecular imaging (2019)

The combination of 18F-FDG-PET/CT and ctDNA quantification is a very promising noninvasive tool for assessing treatment responses and detecting tumor relapses in children and young adolescents suffering from EwS who are undergoing multimodal chemotherapy.

Keyphrases

circulating tumor
young adults
cell free
physical activity
squamous cell carcinoma
radiation therapy
combination therapy
rectal cancer
replacement therapy