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Henoch-Schönlein purpura: Another COVID-19 complication.

Georges El HasbaniAli T TaherAli S M JawadImad Uthman
Published in: Pediatric dermatology (2021)
Whether affecting children or adults, SARS-CoV-2 infection (COVID-19) can have multi-organ involvement mediated by an inflammatory cascade. Immunoglobulin A (IgA) is one of the key components of the inflammatory cascade that can lead to endothelial injury and inflammation. IgA vasculitis or Henoch-Schönlein purpura (HSP) has been rarely reported in the context of COVID-19. In this report, we highlight a case of HSP occurring 2 days after diagnosis of COVID-19 in a 16-year-old boy, who presented with palpable purpura of the lower extremities and buttocks, diffuse abdominal pain, hemoptysis, and hematochezia. He was treated with oral prednisolone with rapid clinical improvement.
Keyphrases
  • coronavirus disease
  • sars cov
  • oxidative stress
  • respiratory syndrome coronavirus
  • abdominal pain
  • heat stress
  • endothelial cells