Exposure to Sodium Valproate during Pregnancy: Facial Features and Signs of Autism.

Rachel T StadelmaierHanah NasriCurtis K DeutschMargaret BaumanAnne HuntChristopher J StodgellJane AdamsLewis B Holmes

Published in: Birth defects research (2017)

An increased frequency of dysmorphic craniofacial features was identified in children exposed to VPA during the first trimester of pregnancy. The most consistent finding was a larger cephalic index, which indicates a disproportion of increased width of the skull relative to the shortened anterior-posterior length. Birth Defects Research 109:1134-1143, 2017. © 2017 Wiley Periodicals, Inc.

Keyphrases

autism spectrum disorder
young adults
pregnancy outcomes
intellectual disability
preterm birth
gestational age
pregnant women