Differential Effects of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors on Insulin Resistance and β-Cell Function in Type 2 Diabetes Mellitus: A Propensity Score-Matched Analysis.

Jaehyun BaeGyuri KimYong-Ho LeeByung-Wan LeeEun Seok KangBong Soo Cha

Published in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2018)

TZD users showed significantly better insulin sensitivity, whereas DPP-4 inhibitor users secreted more insulin from β-cells under similar glycemic control.

Keyphrases

glycemic control
type diabetes
insulin resistance
blood glucose
induced apoptosis
weight loss
cell cycle arrest
adipose tissue
high fat diet
metabolic syndrome
skeletal muscle
polycystic ovary syndrome
cell death
oxidative stress
endoplasmic reticulum stress
high fat diet induced
signaling pathway