Survival outcomes of patients with brain metastasis of osteosarcoma can be improved by aggressive multi-disciplinary interventions including chemotherapy.
Yan ZhuGentao FanLili CaoHao ZhuSujia WuJianning ZhaoGuangxin ZhouPublished in: British journal of neurosurgery (2021)
This is a retrospective study describing the characteristics of metastasic intervals, locations, clinical features and prognosis in 97 patients with brain metastasis of osteosarcoma (BMO). Multivariate analysis showed that chemotherapy was effective as surgery and radiotherapy for the treatment of BMO. Our findings emphasize the importance of regular neuroimaging and early aggressive multi-disciplinary interventions including surgical resection, postoperative radiotherapy and chemotherapy.
Keyphrases
- locally advanced
- rectal cancer
- squamous cell carcinoma
- radiation therapy
- early stage
- white matter
- physical activity
- resting state
- minimally invasive
- radiation induced
- patients undergoing
- coronary artery bypass
- chemotherapy induced
- multiple sclerosis
- coronary artery disease
- atrial fibrillation
- acute coronary syndrome
- combination therapy
- data analysis
- brain injury