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Do B-1 cells play a role in response to Mycobacterium tuberculosis Beijing lineages?

Fermín AcostaPatricia L FernándezAmador Goodridge
Published in: Virulence (2021)
We highlight the need to include an analysis of the B-1 B cell subset to complement the characterization of the cell-mediated immune response to the Mycobacterium tuberculosis Beijing lineage. The literature describes the B-1 cell repertoire's involvement in the cell-mediated response within granulomas, which is different from the classic antibody response B cells are generally associated with. Specifically, the B-1 B cell subset migrates from other compartments along with other cells to the infection site. We provide details to complement the reported results from Cerezo-Cortes et al.
Keyphrases
  • mycobacterium tuberculosis
  • single cell
  • air pollution
  • cell therapy
  • induced apoptosis
  • systematic review
  • particulate matter
  • pulmonary tuberculosis
  • cell cycle arrest
  • signaling pathway
  • stem cells
  • bone marrow
  • pi k akt