A recombinant Der p 1-specific allergen-toxin demonstrates superior killing of allergen-reactive IgG + hybridomas in comparison to its recombinant allergen-drug conjugate.
A K DaramolaO A AkinrinmadeE A FajemisinKrupa NaranN MthembuS HadebeF BrombacherA M HuysamenO E FadeyiR HunterS BarthPublished in: Immunotherapy advances (2022)
Altogether, the proof-of-concept experiments in this study provide a promising approach for the treatment of patients with house dust mite-driven allergic asthma.