Engagement of vascular early response genes typifies mild cognitive impairment.

Pavel KatselPeter FamWeilun TanSonia KhanMiguel Gama-SosaRita De GasperiPanos RoussosAri RobinsonItzik CooperMichal Schnaider-BeeriVahram Haroutunian

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2021)

These findings suggest that cerebrovascular remodeling is an important antecedent to the development of dementia and a component of the homeostatic response to reduced oxygen tension in aging prior to the onset of AD.

Keyphrases

mild cognitive impairment
cognitive decline
genome wide
social media
bioinformatics analysis
genome wide identification
dna methylation
gene expression