Evaluation of four commercial, fully automated SARS-CoV-2 antibody tests suggests a revision of the Siemens SARS-CoV-2 IgG assay.

Christian IrsaraAlexander E EggerWolfgang ProkopManfred NairzLorin LoackerSabina SahanicAlex PizziniThomas SonnweberWolfgang MayerHarald SchennachJudith Loeffler-RaggRosa Bellmann-WeilerIvan TancevskiGünter WeissMarkus AnlikerAndrea GriesmacherGregor Hoermann

Published in: Clinical chemistry and laboratory medicine (2021)

Thorough on-site evaluation of commercially available serologic tests for detection of antibodies against SARS-CoV-2 remains imperative for laboratories. The potentially impaired sensitivity of the Siemens COV2G necessitates a switch to the company's newly filed SARS-CoV-2 IgG assay for follow-up studies. A combination of tests could be considered in clinical practice.

Keyphrases

sars cov
respiratory syndrome coronavirus
high throughput
clinical practice
machine learning
loop mediated isothermal amplification