Strengthening therapeutic adherence and pharmacovigilance to antimalarial treatment in Manaus, Brazil: a multicomponent strategy using mHealth.
Diego Macías Saint-GeronsSheila RodovalhoÁdila Liliane Barros DiasAndré Lacerda Ulysses de CarvalhoAndrea BeratarrecheaWuelton Marcelo MonteiroMyrna Barata MachadoCristiano Fernandes da CostaMarcelo Yoshito WadaMárcia Helena Maximiano Faria de AlmeidaRayanne Silva de Matos FonsecaJady Shayenne Mota CordeiroAlinne Paula Rodrigues AntoliniJoão Altecir NepomucenoKaren FleckFernanda Simioni GasparottoMarcus LacerdaRobin Rojas-CortésShanthi Narayan PalAnalía I PorrásMaría de la Paz AdeJosé Luis CastroPublished in: Malaria journal (2022)
Under real world conditions, a multicomponent patient-oriented strategy using information and communication technologies allowed health care providers to reinforce treatment adherence and enhance safety surveillance of adverse events associated with regimens using primaquine. Active monitoring through phone surveys also reduced under-reporting of ADRs. This approach is low-cost, scalable and able to support prioritized activities of the national malaria programme.