Low FoxG1 and high Olig-2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)-mutant gliomas.

S SchäferF BehlingM SkardellyM KochI OttF PaulsenG TabatabaiCornelia Brendle

Published in: Neuropathology and applied neurobiology (2017)

While the combined FoxG1/Olig-2 profile may discriminate H3F3A K27- and G34-mutant tumours and define a prognostically favourable subset in IDH-mutant gliomas, our data show that labelling indices of these transcription factors overlap with adult IDH-mutant and wild-type tumour classes.

Keyphrases

wild type
high grade
transcription factor
low grade
young adults