Brain magnetic resonance imaging is a predictor of bimanual performance and executive function in children with unilateral cerebral palsy.
Alison CrichtonMichael DitchfieldStella May GwiniMargaret WallenMegan ThorleyJenny BrackenAdrienne R HarveyCatherine ElliottIona NovakBrian J HoarePublished in: Developmental medicine and child neurology (2020)
Clinical brain MRI predicts cognitive and motor outcomes when focal lesions and predominate lesion patterns are considered. What this paper adds Early brain magnetic resonance imaging (MRI) predicts bimanual performance and cognitive outcomes. Brain MRI may identify children requiring targeted interventions. Basal ganglia with/without thalamic lesions predicted bimanual performance. Frontal lesions were associated with attention control and cognitive flexibility. Brain MRI predominant patterns predicted motor, not cognitive outcomes, other than information processing.
Keyphrases
- magnetic resonance imaging
- cerebral palsy
- contrast enhanced
- resting state
- white matter
- functional connectivity
- diffusion weighted imaging
- computed tomography
- cerebral ischemia
- young adults
- working memory
- magnetic resonance
- physical activity
- drug delivery
- multiple sclerosis
- type diabetes
- metabolic syndrome
- subarachnoid hemorrhage
- blood brain barrier