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Strategy of combining offline 2D LC-MS with LC-DIA-MS/MS to accurately identify chemical compounds and for quality control of Dioscorea septemloba Thunb.

Hongxi ChenLei WangChenxi WangYi ZhangHaiyang YuZhifei FuXuebin FuLi-Feng Han
Published in: Phytochemical analysis : PCA (2022)
Our strategy integrating offline 2D LC-MS and the DIA mode could effectively separate and identify compounds from DST, indicating it can be used in subsequent compounds characterization studies. At the same time, the quality of DST was comprehensively and systematically evaluated.
Keyphrases
  • quality control
  • ms ms
  • mass spectrometry
  • liquid chromatography
  • solid phase extraction