Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer.

Rebeca San Martin Priyojit DasTianchun XueMorgan Rose BrownRenata Dos Reis MarquesMichael EssingtonAdrian GonzalezRachel Patton McCord

Published in: bioRxiv : the preprint server for biology (2023)

To model the role of calcium in the microenvironment of the metastatic bone niche, we developed a cost-effective way to coat cell culture vessels in bioavailable calcium, and show that it has an effect on prostate cancer cell survival.

Keyphrases

prostate cancer
radical prostatectomy
bone mineral density
stem cells
squamous cell carcinoma
small cell lung cancer
soft tissue
bone regeneration
postmenopausal women
bone loss
room temperature
staphylococcus aureus
biofilm formation
pseudomonas aeruginosa
ionic liquid