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Drug-Induced Gingival Overgrowth: A Pilot Study on the Effect of Diphenylhydantoin and Gabapentin on Human Gingival Fibroblasts.

Lauritano DorinaGiulia MoreoLuisa LimongelliElena TregambiAnnalisa PalmieriFrancesco Carinci
Published in: International journal of environmental research and public health (2020)
Data recorded in our study confirmed the hypothesis of a direct action of these drugs at the periodontium level, inducing an increase in matrix production, a reduction in its degradation, and consequently resulting in gingival hyperplasia.
Keyphrases
  • drug induced
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  • endothelial cells
  • electronic health record
  • adverse drug
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  • big data
  • induced pluripotent stem cells
  • extracellular matrix
  • machine learning
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  • deep learning