Drug-Induced Gingival Overgrowth: A Pilot Study on the Effect of Diphenylhydantoin and Gabapentin on Human Gingival Fibroblasts.
Lauritano DorinaGiulia MoreoLuisa LimongelliElena TregambiAnnalisa PalmieriFrancesco CarinciPublished in: International journal of environmental research and public health (2020)
Data recorded in our study confirmed the hypothesis of a direct action of these drugs at the periodontium level, inducing an increase in matrix production, a reduction in its degradation, and consequently resulting in gingival hyperplasia.