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Elevated USP9X drives early-to-late-stage oral tumorigenesis via stabilisation of anti-apoptotic MCL-1 protein and impacts outcome in oral cancers.

Prasad SulkshaneSagar N PawarRohit WagholeSushil S PawarPriyanka RajputAbhay UthaleSwapnil OakPrajakta KalkarHarshada WaniRahul PatilSudhir NairPallavi RaneTanuja Teni
Published in: British journal of cancer (2021)
We demonstrate the oncogenic role of USP9X in driving early-to-late stages of oral tumorigenesis via stabilisation of MCL-1, suggesting its potential as a prognostic biomarker and therapeutic target in oral cancers.
Keyphrases
  • young adults
  • amino acid